Dopamine
Drugs
Nonlegal Drugs
  • Cocaine
  • Marjuana
  • LSD
    • Legal Drugs
    Caffeine: Is an example of in order to understand a drug, must understand macro and micro scale.
  • Nicotine
    • Act on:
  • Ionotropic gated channels (nicotine, alcohol) and
  • Metabatropic gated channels (opioids, cannabis, LSD)
  • Mimick neurotransmitters
    • Sixth Lecture
    Has two pathways in the brain
  • Each pathway has a very different function.
  • Many drugs of abuse increase dopamine release in nucleus accumbens.
  • Gives pleasure of satisfaction
    • Examples
  • Cocaine
  • Extreme example: bath salt (deletes DA re-uptake pump so in the cleft longer, 10X potenency of cocaine)
    • Manufactured Drugs
    Can have severe side effects (ex. Parkinsons)
    Measuring effects of Drugs
    Dendrites
    Length of the dendrites
    Map brain decay
    Or similar brain scan
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