METHOTREXATE

Mechanism of actionhttp://www.youtube.com/watch?v=4_nleHL_SHw
  • Folate analog 
  • inhibits dihydrofolate reductase
  • Tetrahydrofolate is important for Thiamine & Guanosine synthesis

  • Reduces IL-1B in synovial fluid
  • Suppress Cell mediated immunity
  • Inhibits Histamine release
  • Reduce the synthesis Leukotriene B4 in 

Description
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Description
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INDICATIONS
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Description
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