1. Lower urinary tract disease (due to stone formation/urolithiasis); may present with acute pain upon urination, possibly due to metabolic disturbances and/or reduced fluid intake. May lead to renal colic if untreatedÂ
2. Lower urinary tract disease (Infection); possibly due to her drug use, her gender predisposition to acquiring, may be aetiology of elevated temperature. If untreated may lead to renal pelvis/calyx infection)
3. Transitional Cell Carcinoma (of the Bladder); possibly due to smoking, possible genetic predisposition
4. Diabetes Mellitus (T2); may be responsible for her generalised fatigue & more likely due to her weight. If left untreated may result in myocardial infarct, renal failure, cerebrovascular accident or cancers
5. Kidney disorder; may be aetiological factor for her hypertension, which may be contributed to by reduced fluid intake